000			02734cam a22003011a 4500
008			100228s2009 nyu a 001 0 eng
010			_a2008029273
020			_a9780815342151
020			_a _a 0815342152
035			_a(Sirsi) u4018
040			_aEG-CaNU _c EG-CaNU _d EG-CaNU
042			_ancode
082	0	0	_a517.74 _2 22
100	1		_a Marks, Friedrich, _d 1936- _96309
245	1	0	_aCellular signal processing : _b an introduction to the molecular mechanisms of signal transduction / _c Friedrich Marks, Ursula Klingmüller, Karin Müller-Decker.
260			_aNew York : _b Garland Science, _c c2009.
300			_axiii, 634 p. : _b ill. ; _c 28 cm.
504			_aIncludes bibliographical references and index.
505		0	_aThe "brain of the cell" : data processing by protein networks -- Supplying the network with energy : basic biochemistry of signal transduction -- Evolution of cellular data processing -- Basic equipment : G-proteins, second messengers, and protein kinases -- Signal transduction by receptors with seven transmembrane domains -- Signal transduction by serine/threonine kinase-coupled receptors -- Signal transduction by tyrosine kinase- and protein phosphatase-coupled receptors : a late invention of evolution -- Gene transcription : the ultimate target of signal transduction -- Signals controlling mRNA translation -- Signal transduction by small G-proteins : the art of molecular targeting -- Mitogen-activated protein kinase and nuclear factor k̳B modules -- Cancer and regulation of cell division -- Signal transduction by proteolysis and programmed cell death -- Signal transduction by ions -- Sensory signal processing -- Signaling at synapses : neurotransmitters and their receptors -- Putting together the pieces : the approach of systems biology.
520			_aCellular Signal Processing" is intended for use in signal transduction courses for undergraduate and graduate students. It offers a unifying view of cell signaling that is based on the concept of protein interactions acting as sophisticated data processing networks that govern intracellular and extracellular communication. The content is guided by three major principles that are central to signal transduction: the protein network, its energy supply, and its evolution. It includes coverage of all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal.
650		0	_aCellular signal transduction. _97964
650	1	2	_aSignal Transduction _x physiology. _97965
650	2	2	_aIntracellular Signaling Peptides and Proteins _x physiology. _97966
700	1		_aKlingmüller, Ursula. _97967
700	1		_aMüller-Decker, Karin. _92584
920			_a0815342152
596			_a1
999			_c3005 _d3005