TY - BOOK AU - Lynch,Michael TI - The origins of genome architecture / SN - 9780878934843 U1 - 660.65 22 PY - 2007/// CY - Sunderland, Mass. : PB - Sinauer Associates, KW - Bioinformatics KW - Evolutionary genetics KW - Genomes KW - Molecular evolution KW - Population genetics KW - Genome KW - genetics KW - Eukaryotic Cells KW - Evolution, Molecular N1 - Includes bibliographical references (p. [401]-470) and indexes; The origin of eukaryotes -- Genome size and organismal complexity -- The human genome -- Why population size matters -- Three keys to chromosomal integrity -- The nucleotide composition landscape -- Mobile genetic elements -- Genomic expansion by gene duplication -- Genes in pieces -- Transcript production -- Expansion and contraction of organelle genomes -- Sex chromosomes -- Genomfart ER -