Cellular signal processing : an introduction to the molecular mechanisms of signal transduction / Friedrich Marks, Ursula Klingmüller, Karin Müller-Decker.

Includes bibliographical references and index.

The "brain of the cell" : data processing by protein networks -- Supplying the network with energy : basic biochemistry of signal transduction -- Evolution of cellular data processing -- Basic equipment : G-proteins, second messengers, and protein kinases -- Signal transduction by receptors with seven transmembrane domains -- Signal transduction by serine/threonine kinase-coupled receptors -- Signal transduction by tyrosine kinase- and protein phosphatase-coupled receptors : a late invention of evolution -- Gene transcription : the ultimate target of signal transduction -- Signals controlling mRNA translation -- Signal transduction by small G-proteins : the art of molecular targeting -- Mitogen-activated protein kinase and nuclear factor k̳B modules -- Cancer and regulation of cell division -- Signal transduction by proteolysis and programmed cell death -- Signal transduction by ions -- Sensory signal processing -- Signaling at synapses : neurotransmitters and their receptors -- Putting together the pieces : the approach of systems biology.

Cellular Signal Processing" is intended for use in signal transduction courses for undergraduate and graduate students. It offers a unifying view of cell signaling that is based on the concept of protein interactions acting as sophisticated data processing networks that govern intracellular and extracellular communication. The content is guided by three major principles that are central to signal transduction: the protein network, its energy supply, and its evolution. It includes coverage of all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal.

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